BDBM31265 isoindolinone scaffold, 60

SMILES CCCN1C(=O)c2ccccc2C1(OCc1cc2OCOc2cc1[N+]([O-])=O)c1ccc(cc1)C(C)(C)C

InChI Key InChIKey=KCHCPTJMORMXJX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31265   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Newcastle Upon Tyne

LigandPNGBDBM31265(isoindolinone scaffold, 60)
Affinity DataIC50: 7.02E+4nMAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed