BDBM312442 2-[3-(4-Methyl-thiazol-2-yl)-6-trifluoromethyl-4,5,6,7-tetrahydro-benzo[b]thiophen-2-ylcarbamoyl]-cyclopent-1-enecarboxylic acid::US9604977, Example 188

SMILES Cc1csc(n1)-c1c(NC(=O)C2=C(CCC2)C(O)=O)sc2CC(CCc12)C(F)(F)F

InChI Key InChIKey=JFCISRJHIZUEMD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 312442   

TargetFatty acid-binding protein, adipocyte(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM312442(US9604977, Example 188 | 2-[3-(4-Methyl-thiazol-2-...)
Affinity DataIC50: 272nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetFatty acid-binding protein 5(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM312442(US9604977, Example 188 | 2-[3-(4-Methyl-thiazol-2-...)
Affinity DataIC50: 22nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent