BDBM312156 6-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butoxy)-2H-benzo[b][1,4]oxazin-3(4H)-one ::US10441590, Compound A::US12053477, Compound B::US9604944, 15a (Example 13)::US9975862, 15a (Example 13)
SMILES COc1ccccc1N1CCN(CCCCOc2ccc3OCC(=O)Nc3c2)CC1
InChI Key InChIKey=ZQIBMJPPTOOPCH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 312156
Affinity DataIC50: 0.980nMAssay Description:Dopamine, D2S: Materials and Methods: Receptor Source: Human recombinant expressed in CHO cells Radioligand: [3H]Spiperone (20-60 Ci/mmol) Control Co...More data for this Ligand-Target Pair
Affinity DataIC50: 0.970nMAssay Description:Serotonin, 5HT1A:Receptor Source: Human recombinant expressed in HEK-293 cellsRadioligand: [3H]-8-OH-DPAT (221 Ci/mmol)Control Compound: 8-OH-DPATInc...More data for this Ligand-Target Pair
Affinity DataIC50: 262nMAssay Description:Serotonin, 5HT2A :Materials and Methods: Receptor Source: Human Cortex Radioligand: [3H]-Ketanserin (60-90 Ci/mmol) Control Compound: Ketans...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nM IC50: 0.980nMAssay Description:Receptor Source: Human recombinant expressed in CHO cells Radioligand: [3H]Spiperone (20-60 Ci/mmol) Control Compound: Haloperidol Incubatio...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Dopamine, D2S: Materials and Methods: Receptor Source: Human recombinant expressed in CHO cells Radioligand: [3H]Spiperone (20-60 Ci/mmol) Control Co...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Dopamine, D2s: Radioligand: [3H]Spiperone (20-60 Ci/mmol) or [3H]-7-hydroxy DPAT, 1.0 nMControl Compound: Haloperidol or ChlorpromazineIncubation Con...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Receptor Source: Human recombinant D2S expressed mammalian cellsRadioligand: [3H]Spiperone (20-60 Ci/mmol) or [3H]-7-hydroxy DPAT, 1.0 nMControl Comp...More data for this Ligand-Target Pair
Affinity DataKi: 0.650nM IC50: 0.970nMAssay Description:Receptor Source: Human recombinant expressed in HEK-293 cells Radioligand: [3H]-8-OH-DPAT (221 Ci/mmol) Control Compound: 8-OH-DPAT Incubati...More data for this Ligand-Target Pair
Affinity DataKi: 0.650nMAssay Description:Serotonin, 5HT1A:Receptor Source: Human recombinant expressed in HEK-293 cellsRadioligand: [3H]-8-OH-DPAT (221 Ci/mmol)Control Compound: 8-OH-DPATInc...More data for this Ligand-Target Pair
Affinity DataKi: 0.650nMAssay Description:Serotonin, 5HT1A: Materials and Methods:Receptor Source: Human recombinant 5-HT1A expressed mammalian cellsRadioligand: [3H]-8-OH-DPAT (221 Ci/mmol)C...More data for this Ligand-Target Pair
Affinity DataKi: 0.650nMAssay Description:Materials and Methods:Receptor Source: Human recombinant 5-HT1A expressed mammalian cellsRadioligand: [3H]-8-OH-DPAT (221 Ci/mmol)Control Compound: 8...More data for this Ligand-Target Pair
Affinity DataKi: 118nM IC50: 262nMAssay Description:Receptor Source: Human Cortex Radioligand: [3H]-Ketanserin (60-90 Ci/mmol) Control Compound: Ketanserin Incubation Conditions: The reactions...More data for this Ligand-Target Pair
Affinity DataKi: 118nMAssay Description:Serotonin, 5HT2A :Materials and Methods: Receptor Source: Human Cortex Radioligand: [3H]-Ketanserin (60-90 Ci/mmol) Control Compound: Ketans...More data for this Ligand-Target Pair
Affinity DataKi: 118nMAssay Description:Serotonin, 5HT1A: Materials and Methods:Receptor Source: Human recombinant 5-HT1A expressed mammalian cellsRadioligand: [3H]-8-OH-DPAT (221 Ci/mmol)C...More data for this Ligand-Target Pair
Affinity DataKi: 118nMAssay Description:Materials and Methods:Receptor Source: Human Cortex or Human recombinant 5-HT2A expressed mammalian cellsRadioligand: [3H]-Ketanserin (60-90 Ci/mmol)...More data for this Ligand-Target Pair