BDBM312116 (S)-2-((S)-3,3- Dimethyl-2-((S)-2- (methylamino) propanamido) butanoyl)- N-(4-(((3S,5S)-1- ((S)-3,3-dimethyl- 2-((S)-2- (methylamino) propanamido) butanoyl)- 5-(((R)-1,2,3,4- tetrahydro- naphthalen- 1-yl)carbamoyl) pyrrolidin-3-yl) carbamoyl) benzyl)-N-((R)-1- (2-fluorophenyl) propan-2-yl)- 1,2,3,4-tetrahydro- isoquinoline- 1-carboxamide::US9603889, Example 27
SMILES CN[C@@H](C)C(=O)N[C@H](C(=O)N1CC(C[C@H]1C(=O)NC1CCCc2ccccc12)NC(=O)c1ccc(CN([C@H](C)Cc2ccccc2F)C(=O)[C@H]2N(CCc3ccccc23)C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)cc1)C(C)(C)C
InChI Key InChIKey=ZUAAEZJCFHSIOK-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 312116
TargetBaculoviral IAP repeat-containing protein 3/E3 ubiquitin-protein ligase XIAP(Human)
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 90nMAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of N-His-Tb-BIR3(241-356,...More data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2/E3 ubiquitin-protein ligase XIAP(Human)
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 1.74E+3nMAssay Description:Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi...More data for this Ligand-Target Pair