BDBM312086 3-(2,5-dioxopyrrolidin- 3-yl)-1H-indole-6- carbonitrile::US9603836, Compound 22

SMILES O=C1CC(C(=O)N1)c1c[nH]c2cc(ccc12)[N+]#[C-]

InChI Key InChIKey=SLYFGJOULUQQIS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 312086   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM312086(US9603836, Compound 22 | 3-(2,5-dioxopyrrolidin- 3...)
Affinity DataIC50: 1.70E+3nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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