BDBM312078 3-(5-methoxy-1H-indol- 3-yl)pyrrolidine-2,5- dione::US9603836, Compound 13::US9949951, 13

SMILES OCc1ccc2[nH]cc(C3CC(=O)NC3=O)c2c1

InChI Key InChIKey=PIYZASGZELZCSC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 312078   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM312078(US9603836, Compound 13 | 3-(5-methoxy-1H-indol- 3-...)
Affinity DataIC50: 5.30E+4nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM312078(US9603836, Compound 13 | 3-(5-methoxy-1H-indol- 3-...)
Affinity DataIC50: 5.30E+4nMAssay Description:The compounds of the present invention inhibit the enzymatic activity of human IDO1.To measure enzymatic activity of human IDO1, the reaction mixture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2020
Entry Details
Go to US Patent