BDBM312068 2-[(2-Aminoethyl)amino]-N-(3-carbamoyl-1-methyl-1H-pyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazine-7-carboxamide::US9649308, Example 58

SMILES Cn1cc(NC(=O)c2ccc3cnc(NCCN)nn23)c(n1)C(N)=O

InChI Key InChIKey=RIEOQOKFWLOQOT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 312068   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM312068(US9649308, Example 58 | 2-[(2-Aminoethyl)amino]-N-...)
Affinity DataIC50: 0.900nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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