BDBM311942 US10166214, Example 78::US10675268, Example 78::US9789082, Example 78

SMILES Cc1cc2cccnc2c(n1)C(C)(C)NC(=O)[C@@H]1[C@H]2CNC[C@@H]12

InChI Key InChIKey=FQWRCPBHHGUSOD-UHFFFAOYSA-N

Data  15 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 311942   

TargetSomatostatin receptor type 4(Human)
Centrexion Therapeutics

US Patent
LigandPNGBDBM311942(US10166214, Example 78 | US9789082, Example 78 | U...)
Affinity DataEC50:  3.20nMAssay Description:The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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TargetSomatostatin receptor type 4(Human)
Centrexion Therapeutics

US Patent
LigandPNGBDBM311942(US10166214, Example 78 | US9789082, Example 78 | U...)
Affinity DataEC50:  3.20nMAssay Description:The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2021
Entry Details
Go to US Patent

TargetSomatostatin receptor type 4(Human)
Centrexion Therapeutics

US Patent
LigandPNGBDBM311942(US10166214, Example 78 | US9789082, Example 78 | U...)
Affinity DataKi:  97.2nMAssay Description:For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
Go to US Patent

TargetSomatostatin receptor type 4(Human)
Centrexion Therapeutics

US Patent
LigandPNGBDBM311942(US10166214, Example 78 | US9789082, Example 78 | U...)
Affinity DataKi:  97.2nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent

TargetSomatostatin receptor type 4(Human)
Centrexion Therapeutics

US Patent
LigandPNGBDBM311942(US10166214, Example 78 | US9789082, Example 78 | U...)
Affinity DataKi:  97.2nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2021
Entry Details
Go to US Patent

TargetSomatostatin receptor type 1(Human)
Centrexion Therapeutics

US Patent
LigandPNGBDBM311942(US10166214, Example 78 | US9789082, Example 78 | U...)
Affinity DataKi:  6.64E+3nMAssay Description:For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
Go to US Patent

TargetSomatostatin receptor type 1(Human)
Centrexion Therapeutics

US Patent
LigandPNGBDBM311942(US10166214, Example 78 | US9789082, Example 78 | U...)
Affinity DataKi:  6.64E+3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent

TargetSomatostatin receptor type 1(Human)
Centrexion Therapeutics

US Patent
LigandPNGBDBM311942(US10166214, Example 78 | US9789082, Example 78 | U...)
Affinity DataKi:  6.64E+3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2021
Entry Details
Go to US Patent

TargetSomatostatin receptor type 3(Human)
Centrexion Therapeutics

US Patent
LigandPNGBDBM311942(US10166214, Example 78 | US9789082, Example 78 | U...)
Affinity DataKi: >8.71E+3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2021
Entry Details
Go to US Patent

TargetSomatostatin receptor type 3(Human)
Centrexion Therapeutics

US Patent
LigandPNGBDBM311942(US10166214, Example 78 | US9789082, Example 78 | U...)
Affinity DataKi: >8.71E+3nMAssay Description:For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
Go to US Patent

TargetSomatostatin receptor type 3(Human)
Centrexion Therapeutics

US Patent
LigandPNGBDBM311942(US10166214, Example 78 | US9789082, Example 78 | U...)
Affinity DataKi: >8.71E+3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent

TargetSomatostatin receptor type 2(Human)
Centrexion Therapeutics

US Patent
LigandPNGBDBM311942(US10166214, Example 78 | US9789082, Example 78 | U...)
Affinity DataKi: >9.63E+3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent

TargetSomatostatin receptor type 2(Human)
Centrexion Therapeutics

US Patent
LigandPNGBDBM311942(US10166214, Example 78 | US9789082, Example 78 | U...)
Affinity DataKi: >9.63E+3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2021
Entry Details
Go to US Patent

TargetSomatostatin receptor type 2(Human)
Centrexion Therapeutics

US Patent
LigandPNGBDBM311942(US10166214, Example 78 | US9789082, Example 78 | U...)
Affinity DataKi: >9.63E+3nMAssay Description:For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
Go to US Patent

TargetSomatostatin receptor type 5(Human)
Centrexion Therapeutics

US Patent
LigandPNGBDBM311942(US10166214, Example 78 | US9789082, Example 78 | U...)
Affinity DataKi: >9.86E+3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent

TargetSomatostatin receptor type 5(Human)
Centrexion Therapeutics

US Patent
LigandPNGBDBM311942(US10166214, Example 78 | US9789082, Example 78 | U...)
Affinity DataKi: >9.86E+3nMAssay Description:For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
Go to US Patent

TargetSomatostatin receptor type 5(Human)
Centrexion Therapeutics

US Patent
LigandPNGBDBM311942(US10166214, Example 78 | US9789082, Example 78 | U...)
Affinity DataKi: >9.86E+3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2021
Entry Details
Go to US Patent