BDBM311831 7-Chloro-5-[2-cyclopropyl-7-(trifluoromethyl)imidazo[1,2-c]pyrimidin-8-yl]indolin-2-one::US10155769, Example 69

SMILES FC(F)(F)c1ncn2cc(nc2c1-c1cc2CC(=O)Nc2c(Cl)c1)C1CC1

InChI Key InChIKey=KENOPWYIBOIRJE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311831   

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM311831(US10155769, Example 69 | 7-Chloro-5-[2-cyclopropyl...)
Affinity DataIC50: 0.316nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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