BDBM31155 3-hydroxyquinolin-2(1H)-one, 9

SMILES Oc1cc2cc(Cl)ccc2[nH]c1=O

InChI Key InChIKey=PVOGDSMDLVGPKP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 31155   

TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31155(3-hydroxyquinolin-2(1H)-one, 9)
Affinity DataIC50: 155nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandPNGBDBM31155(3-hydroxyquinolin-2(1H)-one, 9)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed