BDBM311545 N-(3-carbamoyl-1-pyridin-3- yl-1H-pyrazol-4-yl)-5- piperazin-1-ylpyrazolo[1,5- a]pyrimidine-3-carboxamide trifluoroacetate::US10155765, Example 36

SMILES NC(=O)c1nn(cc1NC(=O)c1cnn2ccc(nc12)N1CCNCC1)-c1cccnc1

InChI Key InChIKey=SWLJUVKKZQVIGU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311545   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM311545(US10155765, Example 36 | N-(3-carbamoyl-1-pyridin-...)
Affinity DataIC50: 33nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
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Date in BDB:
4/10/2019
Entry Details
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