BDBM311534 5-{[(1R,2S)-2- aminocyclohexyl]amino}- N-[3-carbamoyl-1-(2- hydroxyethyl)-1H- pyrazol-4-yl]pyrazolo[1,5- a]pyrimidine-3- carboxamide trifluoroacetate::US10155765, Example 23

SMILES N[C@H]1CCCC[C@H]1Nc1ccn2ncc(C(=O)Nc3cn(CCO)nc3C(N)=O)c2n1

InChI Key InChIKey=KTZAKGPWQVPVGF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311534   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM311534(US10155765, Example 23 | 5-{[(1R,2S)-2- aminocyclo...)
Affinity DataIC50: 1nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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