BDBM311525 5-[(2- aminoethyl)amino]-N- (3-carbamoyl-1-pyridin- 3-yl-1H-pyrazol-4- yl)pyrazolo[1,5- a]pyrimidine-3- carboxamide::US10155765, Example 11

SMILES NCCNc1ccn2ncc(C(=O)Nc3cn(nc3C(N)=O)-c3cccnc3)c2n1

InChI Key InChIKey=QXVLFHHSHJGJEC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311525   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM311525(US10155765, Example 11 | 5-[(2- aminoethyl)amino]-...)
Affinity DataIC50: 0.700nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
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Date in BDB:
4/10/2019
Entry Details
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