BDBM311233 (S)-4-(4-((2-amino-2,4-dimethylpentyl)oxy)-3-(trifluoromethyl)phenyl)quinoline-7-carbonitrile::US10155760, Example 89

SMILES CC(C)C[C@@](C)(COc1ccc(cc1C(F)(F)F)-c1ccnc2cc(ccc12)[N+]#[C-])NC(=O)OC(C)(C)C

InChI Key InChIKey=CMRHJEQMBABEDZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311233   

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM311233(US10155760, Example 89 | (S)-4-(4-((2-amino-2,4-di...)
Affinity DataIC50: 0.660nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
Go to US Patent