BDBM311151 5-chloro-4-((7-chloro-1-methyl- 1H-indazol-4-yl)oxy)-2-fluoro- N-(1,3,4-thiadiazol-2-yl)- benzenesulfonamide::US10155752, Compound 41::US9834543, Compound 41

SMILES Cn1ncc2c(Oc3cc(F)c(cc3Cl)S(=O)(=O)Nc3nncs3)ccc(Cl)c12

InChI Key InChIKey=RNYUPAUELLXBGU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 311151   

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM311151(US10155752, Compound 41 | 5-chloro-4-((7-chloro-1-...)
Affinity DataIC50: 2.00E+4nMAssay Description:The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM311151(US10155752, Compound 41 | 5-chloro-4-((7-chloro-1-...)
Affinity DataIC50: 2.00E+4nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
Go to US Patent