BDBM310876 3-methyl-6-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-3,4-dihydro-1H-quinoxalin-2-one::US10150767, Example 10

SMILES CC1Nc2cc(ccc2NC1=O)-c1cn(C)c(=O)c2[nH]ccc12

InChI Key InChIKey=OPBFMJUSKPFQLU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 310876   

TargetBromodomain-containing protein 4 [42-168](Human)
Genentech

US Patent
LigandPNGBDBM310876(US10150767, Example 10 | 3-methyl-6-(6-methyl-7-ox...)
Affinity DataIC50: 110nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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