BDBM310770 US10150764, Compound 55

SMILES CCN([C@H]1CC[C@@H](CC1)N(C)CCOC)c1cc(Cl)cc(C(=O)NCc2c(C)n(C)[nH]c2=O)c1C

InChI Key InChIKey=SDCLJXHBASXPSB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 310770   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM310770(US10150764, Compound 55)
Affinity DataIC50: 695nMAssay Description:The assays were performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG, 100 mM KCl and 0.002% Tween20, prepared on the day...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent

LigandPNGBDBM310770(US10150764, Compound 55)
Affinity DataIC50: 418nMAssay Description:The assays were performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG, 100 mM KCl and 0.002% Tween20, prepared on the day...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent