BDBM310755 US10150764, Compound 40

SMILES CCCCc1[nH]n(C)c(=O)c1CNC(=O)c1cc(Cl)cc(N(CC)[C@H]2CC[C@@H](CC2)N(C)C)c1C

InChI Key InChIKey=IYIWRTWWFHWHBC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 310755   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM310755(US10150764, Compound 40)
Affinity DataIC50: 689nMAssay Description:The assays were performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG, 100 mM KCl and 0.002% Tween20, prepared on the day...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent

LigandPNGBDBM310755(US10150764, Compound 40)
Affinity DataIC50: 166nMAssay Description:The assays were performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG, 100 mM KCl and 0.002% Tween20, prepared on the day...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent