BDBM310248 2-(2-cyano-4-fluorophenyl)-N-(4-(2,6-dimethoxyphenyl)-5-((2R)-5-oxo-2-pyrrolidinyl)-4H-1,2,4-triazol-3-yl)ethanesulfonamide::US10150760, Example 43.0

SMILES COc1cccc(OC)c1-n1c(NS(=O)(=O)CCc2ccc(F)cc2C#N)nnc1[C@H]1CCC(=O)N1

InChI Key InChIKey=UNYKKJBYGIXERI-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 310248   

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM310248(US10150760, Example 43.0 | 2-(2-cyano-4-fluorophen...)
Affinity DataEC50:  1.19E+3nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV-3 expression vector (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent