BDBM310115 US10377768, Compound 29::US9657033, Compound 29

SMILES C[C@H](C(=O)Nc1cnc2O[C@@H](C)CN(c2c1)S(=O)(=O)c1ccc(F)cc1)c1ccccc1

InChI Key InChIKey=UYWRVUHPZLEOJE-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 310115   

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM310115(US9657033, Compound 29 | US10377768, Compound 29)
Affinity DataEC50:  3.05E+3nMAssay Description:Recombinant,HIS-tagged RORγ-LBD was expressed in SF9 cells using a baculovirus expression system. Cells were lysed and the lysate was used as a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM310115(US9657033, Compound 29 | US10377768, Compound 29)
Affinity DataEC50:  387nMAssay Description:HIS-tagged RORγ-LBD protein was expressed in SF9 cells using a baculovirus expression system. The RORγ-LBD protein was purified by glutathi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM310115(US9657033, Compound 29 | US10377768, Compound 29)
Affinity DataEC50:  3.05E+3nMAssay Description:Recombinant, HIS-tagged RORγ-LBD was expressed in SF9 cells using a baculovirus expression system. Cells were lysed and the lysate was used as a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM310115(US9657033, Compound 29 | US10377768, Compound 29)
Affinity DataEC50:  387nMAssay Description:HIS-tagged RORγ-LBD protein was expressed in SF9 cells using a baculovirus expression system. The RORγ-LBD protein was purified by glutathi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
Go to US Patent