BDBM310048 US9657015, Example 15.2

SMILES CN1CCC3=C(C1=O)C(c2ccc(C#N)cc2)N(CC(=O)NCCO)C(=O)N3c4cccc(C(F)(F)F)c4

InChI Key InChIKey=NYFYYQZWVYEWKN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 310048   

TargetNeutrophil elastase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 310048BDBM310048(US9657015, Example 15.2)
Affinity DataIC50: 2.70nMAssay Description:Materials: Human neutrophil elastase was purchased from Calbiochem (Cat. No.: 324681) and the elastase substrate MeOSuc-Ala-Ala-Pro-Val-AMC from Bach...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent