BDBM309982 (S)-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(2-methylthiazol-4-yl)-1H-pyrazole-3-carboxamide::US11046713, Example 94::US9657003, 94

SMILES C[C@@H](Cn1ccc(n1)-c1ccc(C#N)c(Cl)c1)NC(=O)c1cc([nH]n1)-c1csc(C)n1

InChI Key InChIKey=OJTYLFHWYLKKCX-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 309982   

TargetAndrogen receptor(Human)
Orion

US Patent
LigandPNGBDBM309982(US9657003, 94 | (S)-N-(1-(3-(3-chloro-4-cyanopheny...)
Affinity DataIC50: 57nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent

TargetAndrogen receptor(Human)
Orion

US Patent
LigandPNGBDBM309982(US9657003, 94 | (S)-N-(1-(3-(3-chloro-4-cyanopheny...)
Affinity DataIC50: 57nMAssay Description:Antagonism of test compounds for AR was measured by reporter gene assay in human embryonic kidney (HEK293) cells stably transfected with an expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
Go to US Patent

TargetAndrogen receptor(Human)
Orion

US Patent
LigandPNGBDBM309982(US9657003, 94 | (S)-N-(1-(3-(3-chloro-4-cyanopheny...)
Affinity DataKi:  8nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent

TargetAndrogen receptor(Human)
Orion

US Patent
LigandPNGBDBM309982(US9657003, 94 | (S)-N-(1-(3-(3-chloro-4-cyanopheny...)
Affinity DataKi:  8nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
Go to US Patent