BDBM309936 1-(1H-benzo[d]- imidazol-5-yl)-3- ((S)-1-(4- methoxyphenyl)- ethyl)thiourea::US9656991, 50

SMILES COc1ccc(cc1)[C@H](C)NC(=S)Nc1ccc2[nH]cnc2c1

InChI Key InChIKey=BGDPLMXMUSEZNY-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 309936   

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

US Patent
LigandPNGBDBM309936(US9656991, 50 | 1-(1H-benzo[d]- imidazol-5-yl)-3- ...)
Affinity DataIC50: 8.32E+3nMAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

US Patent
LigandPNGBDBM309936(US9656991, 50 | 1-(1H-benzo[d]- imidazol-5-yl)-3- ...)
Affinity DataKi:  1.21E+3nMAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent