BDBM309934 1-(3,4- difluorobenzyl)-3- (1H-benzo[d]- imidazol-5- yl)thiourea::US9656991, 48

SMILES Fc1ccc(CNC(=S)Nc2ccc3[nH]cnc3c2)cc1F

InChI Key InChIKey=KCIYLIQFHAUNAM-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 309934   

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

US Patent
LigandPNGBDBM309934(US9656991, 48 | 1-(3,4- difluorobenzyl)-3- (1H-ben...)
Affinity DataIC50: 1.15E+4nMAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

US Patent
LigandPNGBDBM309934(US9656991, 48 | 1-(3,4- difluorobenzyl)-3- (1H-ben...)
Affinity DataKi:  1.50E+3nMAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent