BDBM309930 1-(2,4- dichlorobenzyl)-3- (1H-benzo[d]- imidazol-5- yl)thiourea::US9656991, 44

SMILES Clc1ccc(CNC(=S)Nc2ccc3[nH]cnc3c2)c(Cl)c1

InChI Key InChIKey=AJBNFRFYWBBRMS-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 309930   

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

US Patent
LigandPNGBDBM309930(US9656991, 44 | 1-(2,4- dichlorobenzyl)-3- (1H-ben...)
Affinity DataIC50: 5.68E+3nMAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

US Patent
LigandPNGBDBM309930(US9656991, 44 | 1-(2,4- dichlorobenzyl)-3- (1H-ben...)
Affinity DataKi:  699nMAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent