BDBM309917 1-(3,4- dimethoxyphenyl)-3- (4-(5-methyl-1H- imidazol-1- yl)butyl)thiourea::US9656991, 31

SMILES COc1ccc(NC(=S)NCCCCn2cncc2C)cc1OC

InChI Key InChIKey=KBMZNLWAEWCLAY-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 309917   

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

US Patent
LigandPNGBDBM309917(US9656991, 31 | 1-(3,4- dimethoxyphenyl)-3- (4-(5-...)
Affinity DataIC50: 650nMAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

US Patent
LigandPNGBDBM309917(US9656991, 31 | 1-(3,4- dimethoxyphenyl)-3- (4-(5-...)
Affinity DataKi:  27nMAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent