BDBM309915 1-(1H- benzo[d]imidazol-5- yl)-3-(3,5- dimethoxyphenyl)thio- urea::US9656991, 29

SMILES COc1cc(NC(=S)Nc2ccc3[nH]cnc3c2)cc(OC)c1

InChI Key InChIKey=YIWWFEWFVCKFNY-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 309915   

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

US Patent
LigandPNGBDBM309915(US9656991, 29 | 1-(1H- benzo[d]imidazol-5- yl)-3-(...)
Affinity DataIC50: 1.93E+4nMAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

US Patent
LigandPNGBDBM309915(US9656991, 29 | 1-(1H- benzo[d]imidazol-5- yl)-3-(...)
Affinity DataKi:  2.04E+3nMAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent