BDBM309911 1- (benzo[c][1,2,5]thia- diazol-4-yl)-3-(1H- benzo[d]imidazol-5- yl)thiourea::US9656991, 25

SMILES S=C(Nc1ccc2[nH]cnc2c1)Nc1cccc2nsnc12

InChI Key InChIKey=OTCCXULJKWMXTH-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 309911   

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

US Patent
LigandPNGBDBM309911(US9656991, 25 | 1- (benzo[c][1,2,5]thia- diazol-4-...)
Affinity DataIC50: 1.69E+4nMAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

US Patent
LigandPNGBDBM309911(US9656991, 25 | 1- (benzo[c][1,2,5]thia- diazol-4-...)
Affinity DataKi:  1.86E+3nMAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent