BDBM309898 1-(4- methoxybenzyl)-3- (1H- benzo[d]imidazol-5- yl)thiourea::US9656991, 12

SMILES COc1ccc(CNC(=S)Nc2ccc3[nH]cnc3c2)cc1

InChI Key InChIKey=GSLXCNZXJTWJTJ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 309898   

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

US Patent
LigandPNGBDBM309898(US9656991, 12 | 1-(4- methoxybenzyl)-3- (1H- benzo...)
Affinity DataIC50: 2.66E+3nMAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

US Patent
LigandPNGBDBM309898(US9656991, 12 | 1-(4- methoxybenzyl)-3- (1H- benzo...)
Affinity DataKi:  264nMAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent