BDBM3097 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 64::6-(2,6-dichlorophenyl)-2-({4-[2-(diethylamino)ethoxy]phenyl}amino)-8-ethyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::PD 166285 analog::pyrido[2,3-d]pyrimidin-7-one deriv. 2b

SMILES CCN(CC)CCOc1ccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(CC)c3n2)cc1

InChI Key InChIKey=VYSNYHPSOJCNIW-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 3097   

TargetPlatelet-derived growth factor receptor beta(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3097(6-(2,6-dichlorophenyl)-2-({4-[2-(diethylamino)etho...)
Affinity DataIC50: 150nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2005
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3097(6-(2,6-dichlorophenyl)-2-({4-[2-(diethylamino)etho...)
Affinity DataIC50: 30nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3097(6-(2,6-dichlorophenyl)-2-({4-[2-(diethylamino)etho...)
Affinity DataIC50: 17nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3097(6-(2,6-dichlorophenyl)-2-({4-[2-(diethylamino)etho...)
Affinity DataIC50: 150nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2005
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3097(6-(2,6-dichlorophenyl)-2-({4-[2-(diethylamino)etho...)
Affinity DataIC50: 30nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3097(6-(2,6-dichlorophenyl)-2-({4-[2-(diethylamino)etho...)
Affinity DataIC50: 17nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2005
Entry Details Article
PubMed