BDBM309468 (2R,4S)-5-biphenyl-4-yl-2-methyl-4-[(1H-tetrazole-5-carbonyl)-amino]-pentanoic acid::US9603819, Example 13-1

SMILES C[C@H](C[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)c1nnnn1Cc1ccccc1)C(=O)OCc1ccccc1

InChI Key InChIKey=NOLHAFHPVKYOBZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 309468   

TargetNeprilysin(Human)
Novartis

US Patent
LigandPNGBDBM309468(US9603819, Example 13-1 | (2R,4S)-5-biphenyl-4-yl-...)
Affinity DataIC50: 14nMAssay Description:The activity of a compound according to the present invention can be assessed by the following in vitro & in vivo methods and/or by the following in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent