BDBM308348 US9649309, Compound UNC4113A

SMILES CCCCNc1ncc(c(NC2CCC(O)CC2)n1)-c1ccc(CN2CCN[C@H](C)C2)cn1

InChI Key InChIKey=AOILZWVIBHVMLR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 308348   

TargetTyrosine-protein kinase Mer(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM308348(US9649309, Compound UNC4113A)
Affinity DataIC50: 2.40nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
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TargetGrowth arrest-specific protein 6(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM308348(US9649309, Compound UNC4113A)
Affinity DataIC50: 18nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM308348(US9649309, Compound UNC4113A)
Affinity DataIC50: 5.60nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase receptor TYRO3(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM308348(US9649309, Compound UNC4113A)
Affinity DataIC50: 55nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
Go to US Patent