BDBM308346 US9649309, Compound UNC4111A

SMILES CCCCNc1ncc(c(NC2CCC(O)CC2)n1)-c1ccc(CN2CCNC[C@@H]2C)cn1

InChI Key InChIKey=ZXSGJKRDMSVFSU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 308346   

TargetTyrosine-protein kinase Mer(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM308346(US9649309, Compound UNC4111A)
Affinity DataIC50: 2.5nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
Go to US Patent

TargetGrowth arrest-specific protein 6(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM308346(US9649309, Compound UNC4111A)
Affinity DataIC50: 20nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM308346(US9649309, Compound UNC4111A)
Affinity DataIC50: 6.40nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
Go to US Patent