BDBM308333 US9649309, Compound UNC4240A
SMILES COc1ccc(Nc2ncc(c(N[C@H]3CC[C@H](O)CC3)n2)-c2ccc(CN3CCCC3)cn2)cc1
InChI Key InChIKey=ITRYMWSQXXWWJF-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 308333
Affinity DataIC50: 2.80nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor TYRO3(Human)
University of North Carolina At Chapel Hill
US Patent
University of North Carolina At Chapel Hill
US Patent
Affinity DataIC50: 11nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of North Carolina At Chapel Hill
US Patent
University of North Carolina At Chapel Hill
US Patent
Affinity DataIC50: 2.60nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair