BDBM308319 US9649309, Compound UNC3669A

SMILES CCCCNc1ncc(c(NC2CCC(O)CC2)n1)-c1ccc(cn1)C1(CCC1)N1CCN(C)CC1

InChI Key InChIKey=YTEDDIJNHJDCLR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 308319   

TargetTyrosine-protein kinase Mer(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM308319(US9649309, Compound UNC3669A)
Affinity DataIC50: 2nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase receptor TYRO3(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM308319(US9649309, Compound UNC3669A)
Affinity DataIC50: 26nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
Go to US Patent

TargetGrowth arrest-specific protein 6(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM308319(US9649309, Compound UNC3669A)
Affinity DataIC50: 7.70nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM308319(US9649309, Compound UNC3669A)
Affinity DataIC50: 7.20nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
Go to US Patent