BDBM308182 US9649309, Compound UNC2422A
SMILES CCCCNc1ncc(c(NC2CC[C@H](O)CC2)n1)-c1ccc(CN2CCC(F)(F)CC2)cn1
InChI Key InChIKey=NEZRLVDPFUFEKB-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 308182
Affinity DataIC50: 1.10nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor TYRO3(Human)
University of North Carolina At Chapel Hill
US Patent
University of North Carolina At Chapel Hill
US Patent
Affinity DataIC50: 129nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of North Carolina At Chapel Hill
US Patent
University of North Carolina At Chapel Hill
US Patent
Affinity DataIC50: 7.80nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair