BDBM308067 Intermediate Compound (147)::US9650371, 20

SMILES CC(C)C1=C[C@](C)(N=C(N)S1)c1cc(NC(=O)c2cnc(C)cn2)ccc1F

InChI Key InChIKey=GBQAYAVBZABKHP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 308067   

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandPNGBDBM308067(Intermediate Compound (147) | US9650371, 20)
Affinity DataIC50: 95nMAssay Description:48.5 uL of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) was added to each well of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
Go to US Patent