BDBM308062 US10011593, Ex. 13::US9650366, 13

SMILES Nc1ncc(cc1-c1cc2cc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)ccc2s1)-c1ncccn1

InChI Key InChIKey=NAHXLVLQTLEINO-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 308062   

LigandPNGBDBM308062(US9650366, 13 | US10011593, Ex. 13)
Affinity DataIC50: 558nMAssay Description:PKR: Commercially available recombinant human GST-PKR (SignalChem, Canada; 1.5 uM-2 uM stock) is diluted to 500 nM in assay buffer (20 mM Tris-HCl, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
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LigandPNGBDBM308062(US9650366, 13 | US10011593, Ex. 13)
Affinity DataKi:  558nMAssay Description:Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
Go to US Patent