BDBM308045 (R)-1-(1H- benzo[d]imidazol-5-yl)-5-(4- propoxyphenyl)imidazolidin- 2-one::US9650362, 13

SMILES CCCOc1ccc(cc1)[C@@H]1CNC(=O)N1c1ccc2[nH]cnc2c1

InChI Key InChIKey=XHIKZWOEFZENIX-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 308045   

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

US Patent
LigandPNGBDBM308045(US9650362, 13 | (R)-1-(1H- benzo[d]imidazol-5-yl)-...)
Affinity DataIC50: 3.02E+4nMAssay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30° C. QC activity was evaluated fluorometrical...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
Go to US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

US Patent
LigandPNGBDBM308045(US9650362, 13 | (R)-1-(1H- benzo[d]imidazol-5-yl)-...)
Affinity DataKi:  7.25E+3nMAssay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30° C. QC activity was evaluated fluorometrical...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
Go to US Patent