BDBM308028 (3R)-N-{5-chloro-4-[1-(thiophen-2-ylmethyl)-1H-benzimidazol-6-yl]pyridin-2-yl}piperidine-3-carboxamide::US9650358, Example 324

SMILES Clc1cnc(NC(=O)[C@@H]2CCCNC2)cc1-c1ccc2ncn(Cc3cccs3)c2c1

InChI Key InChIKey=HGOMUEBMPLDRCM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 308028   

TargetCyclin-dependent kinase 9(Human)
Abbvie

US Patent
LigandPNGBDBM308028(US9650358, Example 324 | (3R)-N-{5-chloro-4-[1-(t...)
Affinity DataIC50: 27nMAssay Description:CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
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