BDBM307704 US9650336, Example 7

SMILES CC1(C)COc2ccc(cc2C11C=C(F)C(N)=N1)-c1cncc(F)c1

InChI Key InChIKey=ALCREUZUGAFBCP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 307704   

TargetBeta-secretase 1 [1-460](Human)
Astrazeneca

US Patent
LigandPNGBDBM307704(US9650336, Example 7)
Affinity DataIC50: 770nMAssay Description:The cDNA for the soluble part of the human 13-Secretase (AA 1-AA 460) was cloned using the ASP2-Fc10-1-IRES-GFP-neoK mammalian expression vector. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
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