BDBM30746 1-[4,6-bis(p-anisidino)-s-triazin-2-yl]-4,5-dimethyl-3-pyrazolin-3-one::2-[4,6-bis(4-methoxyanilino)-1,3,5-triazin-2-yl]-3,4-dimethyl-1H-pyrazol-5-one::2-[4,6-bis[(4-methoxyphenyl)amino]-1,3,5-triazin-2-yl]-3,4-dimethyl-1H-pyrazol-5-one::MLS000039261::SMR000035359::cid_660800

SMILES COc1ccc(Nc2nc(Nc3ccc(OC)cc3)nc(n2)-n2[nH]c(=O)c(C)c2C)cc1

InChI Key InChIKey=CHBYZRJINZCOBD-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 30746   

Target5-hydroxytryptamine receptor 1A(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM30746(2-[4,6-bis(4-methoxyanilino)-1,3,5-triazin-2-yl]-3...)
Affinity DataEC50:  9.90E+4nMpH: 7.4 T: 2°CAssay Description:A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2009
Entry Details
PCBioAssay
TargetSphingosine 1-phosphate receptor 3(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM30746(2-[4,6-bis(4-methoxyanilino)-1,3,5-triazin-2-yl]-3...)
Affinity DataEC50:  1.47E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Networ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2011
Entry Details
PCBioAssay
TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM30746(2-[4,6-bis(4-methoxyanilino)-1,3,5-triazin-2-yl]-3...)
Affinity DataEC50:  2.23E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2011
Entry Details
PCBioAssay
TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM30746(2-[4,6-bis(4-methoxyanilino)-1,3,5-triazin-2-yl]-3...)
Affinity DataEC50: >3.00E+5nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay