BDBM306729 BDBM306730::N-(2-(4- ((1R,3R)-2- (2,3-difluoro- propyl)- 3-methyl- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1-yl)- 3,5-difluoro- phenoxy) ethyl)-3- fluoropropan- 1-amine::US10149839, Example 15
SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1C[C@H](F)CF)c1c(F)cc(OCCNCCCF)cc1F
InChI Key InChIKey=BLUQOUAMBBCHSV-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 306729
Affinity DataIC50: 1.70nMAssay Description:Compounds were dosed directly from a compound source microplate containing serially diluted compound (4 wells containing 10 mM, 0.1 mM, 1 mM and 10 n...More data for this Ligand-Target Pair
Affinity DataIC50: 0.370nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Compounds were dosed directly from a compound source microplate containing serially diluted compound (4 wells containing 10 mM, 0.1 mM, 1 mM and 10 n...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair