BDBM3050 2-Amino-6-(2,6-dichlorophenyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one::2-amino-6-(2,6-dichlorophenyl)-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 2::CHEMBL49596::PD 166285 analog

SMILES Cn1c2nc(N)ncc2cc(-c2c(Cl)cccc2Cl)c1=O

InChI Key InChIKey=CWCLGIJGJSHBLC-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 3050   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3050(2-Amino-6-(2,6-dichlorophenyl)-8-methylpyrido[2,3-...)
Affinity DataIC50: 260nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3050(2-Amino-6-(2,6-dichlorophenyl)-8-methylpyrido[2,3-...)
Affinity DataIC50: 260nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Chicken)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM3050(2-Amino-6-(2,6-dichlorophenyl)-8-methylpyrido[2,3-...)
Affinity DataIC50: 260nMAssay Description:Inhibition of chicken c-Src tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3050(2-Amino-6-(2,6-dichlorophenyl)-8-methylpyrido[2,3-...)
Affinity DataIC50: 1.30E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2005
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3050(2-Amino-6-(2,6-dichlorophenyl)-8-methylpyrido[2,3-...)
Affinity DataIC50: 1.30E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3050(2-Amino-6-(2,6-dichlorophenyl)-8-methylpyrido[2,3-...)
Affinity DataIC50: 3.80E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM3050(2-Amino-6-(2,6-dichlorophenyl)-8-methylpyrido[2,3-...)
Affinity DataIC50: 4.87E+3nMAssay Description:Inhibitory concentration of compound against mouse Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3050(2-Amino-6-(2,6-dichlorophenyl)-8-methylpyrido[2,3-...)
Affinity DataIC50: 4.90E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM3050(2-Amino-6-(2,6-dichlorophenyl)-8-methylpyrido[2,3-...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM3050(2-Amino-6-(2,6-dichlorophenyl)-8-methylpyrido[2,3-...)
Affinity DataIC50: 5.60E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2005
Entry Details Article
PubMed