BDBM30494 1,1-dioxoisothiazole analog., 38

SMILES CC(C)(C)CCN1[C@H](C(=O)C(C1=O)=C1NS(=O)(=O)c2c1cccc2OCc1ncon1)C(C)(C)C

InChI Key InChIKey=YTQUYXSECKRTBM-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 30494   

TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandPNGBDBM30494(1,1-dioxoisothiazole analog., 38)
Affinity DataIC50: 650nM EC50:  2.00E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2009
Entry Details Article
PubMed