BDBM30470 1,1-dioxoisothiazole analog., 14

SMILES CCOc1cccc2C(NS(=O)(=O)c12)=C1C(=O)[C@H](C(C)C)N(Cc2ccccc2)C1=O

InChI Key InChIKey=IDNMPKRZSPPZHL-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 30470   

TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandPNGBDBM30470(1,1-dioxoisothiazole analog., 14)
Affinity DataIC50: 3.60E+3nM EC50:  1.80E+4nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2009
Entry Details Article
PubMed