BDBM30469 1,1-dioxoisothiazole analog., 3

SMILES CC(C)[C@@H]1N(Cc2ccccc2)C(=O)C(C1=O)=C1NS(=O)(=O)c2ccccc12

InChI Key InChIKey=OGGSMZUAXVKGDD-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 30469   

TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandPNGBDBM30469(1,1-dioxoisothiazole analog., 3)
Affinity DataIC50: 1.40E+3nM EC50:  2.40E+4nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2009
Entry Details Article
PubMed