BDBM30452 Hexahydro-pyrrolo[1,2-b]pyridazin-2-one, 3::hexahydro-pyrrolo[1,2-b]pyridazin-2-one, 4c

SMILES CC(C)(C)CCN1N2CCCC2C(=O)C(C2=Nc3ccc(NS(C)(=O)=O)cc3S(=O)(=O)N2)C1=O

InChI Key InChIKey=DBFDYTLBZXGCSP-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 30452   

TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandPNGBDBM30452(Hexahydro-pyrrolo[1,2-b]pyridazin-2-one, 3 | hexah...)
Affinity DataIC50: 10nM EC50:  34nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandPNGBDBM30452(Hexahydro-pyrrolo[1,2-b]pyridazin-2-one, 3 | hexah...)
Affinity DataIC50: 10nM EC50:  34nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandPNGBDBM30452(Hexahydro-pyrrolo[1,2-b]pyridazin-2-one, 3 | hexah...)
Affinity DataIC50: 25nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed