BDBM3043 3-{23-methyl-12,14-dioxo-3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tricosa-1(16),2(10),4(9),5,7,11(15),17,19,21-nonaen-3-yl}propanenitrile::Indolocarbazole deriv. 3k

SMILES Cn1c2ccccc2c2c3C(=O)NC(=O)c3c3c4ccccc4n(CCC#N)c3c12

InChI Key InChIKey=KFLRQWPBYVKYGU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 3043   

TargetMyosin light chain kinase, smooth muscle(Chicken)
Tumor Biology Center

LigandPNGBDBM3043(3-{23-methyl-12,14-dioxo-3,13,23-triazahexacyclo[1...)
Affinity DataIC50: 55nMpH: 7.2 T: 2°CAssay Description:The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2005
Entry Details Article

TargetProtein kinase C beta type(Rat)
Tumor Biology Center

LigandPNGBDBM3043(3-{23-methyl-12,14-dioxo-3,13,23-triazahexacyclo[1...)
Affinity DataIC50: 38nMAssay Description:The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2005
Entry Details Article

LigandPNGBDBM3043(3-{23-methyl-12,14-dioxo-3,13,23-triazahexacyclo[1...)
Affinity DataIC50: 3.00E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2005
Entry Details Article

TargetcGMP-dependent protein kinase 1(Bovine)
Tumor Biology Center

LigandPNGBDBM3043(3-{23-methyl-12,14-dioxo-3,13,23-triazahexacyclo[1...)
Affinity DataIC50: 7.20E+3nMAssay Description:The activity of cGPK, activated by cGMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2005
Entry Details Article

TargetMyosin light chain kinase, smooth muscle(Human)
Tumor Biology Center

LigandPNGBDBM3043(3-{23-methyl-12,14-dioxo-3,13,23-triazahexacyclo[1...)
Affinity DataIC50: 55nMAssay Description:The activity of cGPK, activated by cGMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2005
Entry Details Article