BDBM304140 USRE47141, Example 64

SMILES Cc1cccc(n1)-c1[nH]c(CNc2cccc(C#N)c2[N+]#[C-])nc1-c1ccc2ncnn2c1

InChI Key InChIKey=RMHWQFUISDEBBD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 304140   

TargetTGF-beta receptor type-1(Human)
Ewha University—Industry Collaboration Foundation

US Patent
LigandPNGBDBM304140(USRE47141, Example 64)
Affinity DataIC50: 20.6nMAssay Description:ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent